BackgroundThe cell cycle is a critical mechanism for proper cellular growth, development and viability.The p16INK4a and p21Waf1/Cip1 are important regulators of the cell cycle progression in response to internal and external stimuli (e.g., stress).Accumulating evidence indicates that the prefrontal cortex (PFC) is particularly vulnerable to stress,
Integrating embedded systems into next-generation vehicles is proliferating as they increase safety, efficiency, and driving comfort.These functionalities are provided by hundreds of electronic control units (ECUs) that communicate with each other using various protocols that, if not properly designed, may be vulnerable to local or remote attacks.T
The use of animal-borne cameras enables scientists to observe behaviours and interactions that have until now, gone unseen or rarely documented.Researchers can now analyse prey preferences and predator-prey interactions with a new level of detail.New technology allows researchers to analyse prey features before they are captured, adding a new dimen
In this study, the precise orbit determination (POD) software is developed for optical observation.To improve the performance of the estimation algorithm, a nonlinear batch filter, based on the unscented transform (UT) that overcomes the disadvantages of the least-squares (LS) batch filter, is utilized.The LS and UT batch filter algorithms 2018 nis
ABSTRACT Objective: Many biologic agents cause some degree of immunosuppression, which can increase the risk of reactivation of tuberculosis infection (TBI).This risk is variable between individual biologics.We aimed to assess current (and recommended) clinical practice of TBI screening and treatment among patients initiating treatment with biologi